Recent advances in applications of cellulose derivatives-based composite membranes with hydroxyapatite

This review examines the development and application of composite membranes based on cellulose derivatives, particularly cellulose acetate, combined with hydroxyapatite. It explores how the favorable properties of cellulose acetate, including biocompatibility, processability, and hydrophilicity, can be enhanced through the incorporation of hydroxyapatite particles.

The article discusses membrane fabrication methods such as phase inversion, electrospinning, and electrostatic assembly, while highlighting the structural interactions between cellulose-based matrices and hydroxyapatite that influence membrane performance across environmental and biomedical applications.

The review shows that cellulose acetate–hydroxyapatite composite membranes can deliver improved functionality in water purification, tissue engineering, wound healing, controlled drug delivery, and hemodialysis. Hydroxyapatite enhances properties such as adsorption capacity, bioactivity, hydrophilicity, permeability, and cell compatibility, while cellulose acetate provides a versatile and renewable membrane platform. The authors identify particle dispersion and control of membrane structure as important challenges, but conclude that these composites offer significant potential for advanced filtration and healthcare technologies. The findings are particularly relevant for researchers and product developers seeking sustainable, bio-based materials that combine separation performance with biological functionality.

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