Additives incorporated in cellulose acetate membranes to improve its performance as a barrier in periodontal treatment

The study evaluates changes in membrane morphology, structure, thermal behavior, mechanical properties, swelling capacity, and degradation under physiological conditions, with the goal of creating materials better suited for supporting tissue regeneration in the oral environment. 

The findings show that modified cellulose acetate membranes become more porous, more hydrophilic, and exhibit greater interaction with physiological fluids than unmodified cellulose acetate. The combination of both additives produced the most pronounced effects, increasing membrane thickness and porosity while promoting controlled long-term degradation. Although some mechanical properties decreased, the membranes retained sufficient strength for potential periodontal applications and maintained characteristics considered important for tissue regeneration. These results highlight how targeted modification of cellulose acetate can tailor its performance for biomedical uses, supporting the development of bio-based, degradable barrier materials for regenerative dentistry and providing a foundation for further research into advanced cellulose acetate medical devices.

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